"Bust It Baby" is a single by American rapper Plies released on January 25, 2008, and is the first single from Plies' second album, Definition of Real. The original was featured as a bonus track on Definition of Real, while "Bust It Baby Pt. 2", which features R&B singer Ne-Yo, is an official track on the album. The song features a noticeable sample of Janet Jackson's 1990 single "Come Back to Me", a #2 hit from her 1989 album "Janet Jackson's Rhythm Nation 1814". Jackson is also featured on the song's official remix.