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About: BxPC-3     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Thing, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

BxPC-3 (BxPC3) is a human pancreatic cancer cell line used in the study of pancreatic adenocarcinomas and treatments thereof. BxPC-3 cells were derived from a 61-year-old female in 1986, and were confirmed to be tumorigenic in athymic nude mice, with moderate differentiation. The cells produce mucin, and exhibit an epithelial morphology. BxPC-3 cells lack a KRAS mutation, though it is commonly found in pancreatic cancers. BcPC-3 cells, along with JoPaca-1 cells, have high expression of cancer stem cell markers.