About: Candocuronium iodide     Goto   Sponge   NotDistinct   Permalink

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Candocuronium iodide (INN, formerly chandonium, HS-310) is an aminosteroid neuromuscular-blocking drug. Its use in anesthesia for endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India. However, further development was discontinued due to attendant cardiovascular effects, primarily tachycardia that was about the same as the clinically established pancuronium bromide. Candocuronium demonstrated a short duration and a rapid onset of action, with little or no ganglion blocking activity, with a greater potency than pancuronium.

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  • كاندوكورونيوم إيوديد (ar)
  • Candocuronium iodide (en)
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  • كاندوكورونيوم إيوديد أو كاندوكورونيوم يوديد (بالإنجليزية: Candocuronium iodide)‏ هو مركب كيميائي من مجموعة الأمينوستيرويد يستخدم كدواء مرخي للعضلات يتم استخدامه كمساعد في التخدير لتسهيل التنبيب الرغامي ولتوفير استرخاء للعضلات الهيكلية أثناء الجراحة أو التهوية الميكانيكية لفترة وجيزة في الدراسات السريرية في الهند، ولكن توقف التطوير الإضافي للمركب بسبب التأثيرات القلبية الوعائية المصاحبة له، مثل تسرع نبضات القلب في المقام الأول. يعتبر من الحاجبات العصبية العضلية الغير مزيلة للاستقطاب قصيرة المفعول. (ar)
  • Candocuronium iodide (INN, formerly chandonium, HS-310) is an aminosteroid neuromuscular-blocking drug. Its use in anesthesia for endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India. However, further development was discontinued due to attendant cardiovascular effects, primarily tachycardia that was about the same as the clinically established pancuronium bromide. Candocuronium demonstrated a short duration and a rapid onset of action, with little or no ganglion blocking activity, with a greater potency than pancuronium. (en)
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  • Discontinued from clinical development (en)
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