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About: Caspofungin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatAminesyago:Abstraction100002137yago:AliphaticCompound114601294yago:Amide114724264yago:Amine114739004yago:Chemical114806838yago:Compound114818238yago:Material114580897yago:Matter100020827yago:MethaneSeries114951377yago:OrganicCompound114727670yago:Part113809207yago:Peptide114743046yago:Phenol114989545yago:PhysicalEntity100001930yago:Relation100031921drugyago:Substance100019613yago:WikicatPeptidesyago:WikicatPhenolsumbel-rc:DrugProduct New Facet based on Instances of this Class

Caspofungin (INN) (brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.Caspofungin is administered intravenously.