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About: Centrocone     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Thing100002452, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: yago:WikicatOrganellesyago:BodyPart105220461yago:Organ105297523yago:Organelle105445668yago:Part109385911yago:PhysicalEntity100001930buildingyago:Thing100002452 New Facet based on Instances of this Class

Centrocones are sub-cellular structures involved in the cell division of apicomplexan parasites. Centrocones are a nuclear sub-compartment in parasites of Taxoplasma gondii that work in apposition with the centrosome to coordinate the budding process in mitosis. The centrocone concentrates and organizes various regulatory factors involved in the early stages of mitosis, including the ECR1 and TgCrk5 proteins. The membrane occupation and recognition nexus 1 (MORN1) protein is also contained in this structure and is linked to human diseases, though not much is yet known about the connection between the centrocone and the MORN1 protein.