Lieutenant Colonel Sir Charles George McDonald KCMG KBE KCSG FRCP (25 March 1892 – 23 April 1970) was an Australian physician, army officer and academic. He was noted for his work as a physician in the field of Tuberculosis and during the Second World War served in Greece and Palestine as a lieutenant colonel in the Australian Imperial Force. On his return to Australia, he served in various academic positions culminating in his appointment as Chancellor of the University of Sydney in 1964.