The Cherry Valley National Wildlife Refuge is a National Wildlife Refuge in Monroe County, Pennsylvania. Pennsylvania’s Cherry Valley is rich in natural resources and wildlife diversity. flows through southern Monroe County in northeastern Pennsylvania, flowing into the Delaware River. For generations, local landowners and conservation organizations safeguarded the valley’s clean waters and important natural communities. Recent rapid residential and commercial growth in Monroe County, however, has outpaced efforts to protect these resources. The county is within a two-hour drive of millions of people.