Chlorella autotrophica, or Chlorella sp. (580), is a species of euryhaline, unicellular microalga in the Division Chlorophyta. It is found in brackish waters and was first isolated in 1956 by Ralph A. Lewin. The species is defined by its inability to use organic carbon as a food source, making the species an obligate autotroph. It is sometimes considered a variety of Chlorella vulgaris.
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