Clarksville Methodist Church is a historic church building at 334 Main Street in Clarksville, Tennessee. Currently, the building isn't used as a church. The church was built in 1831, the first permanent church building in Clarksville and one of the city's first brick buildings. In the 1880s, it ceased being used as a church and was converted into residential apartments. It is the only church building in Clarksville that was built before 1850 and is still standing.