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About: Clostridium perfringens beta toxin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Toxin115034074, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: yago:WikicatBacterialToxinsyago:BacterialToxin115034939yago:Matter100020827yago:PhysicalEntity100001930yago:Poison115032376proteinyago:Substance100020090yago:Toxin115034074 New Facet based on Instances of this Class

Clostridium perfringens beta toxin is one of the four major lethal protein toxins produced by Clostridium perfringens Type B and Type C strains. It is a necrotizing agent and it induces hypertension by release of catecholamine. It has been shown to cause necrotic enteritis in mammals and induces necrotizing intestinal lesions in the rabbit ileal loop model. C. perfringens beta toxin is susceptible to breakdown by proteolytic enzymes, particularly trypsin. Beta toxin is therefore highly lethal to infant mammals because of trypsin inhibitors present in the colostrum.