Clyde V. Lee (February 11, 1908 – December 12, 1995) was an American football player and coach. He served as the head football coach at the University of Houston from 1948 to 1954, guiding the Cougars to a 37–32–2 record. Lee played his college career at Centenary College from 1930 to 1932 under Homer Norton. Among his college teammates was Lovette Hill, who later served as his colleague at Houston on his coaching staff and as head baseball coach for the school.