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About: Collagenase clostridium histolyticum     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatDrugsActingOnTheMusculoskeletalSystem, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:Agent114778436yago:CausalAgent100007347yago:Drug103247620yago:Matter100020827yago:PhysicalEntity100001930drugproteinyago:Substance100020090yago:WikicatDrugsActingOnTheMusculoskeletalSystem New Facet based on Instances of this Class

Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen. It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis. BioSpecifics Technologies developed the preparation, which is manufactured and marketed by Endo Pharmaceuticals as Xiaflex in the US and by Sobi as Xiapex in Europe.