Cooleemee (/ˈkuːlɪmiː/), also known as the Cooleemee Plantation House, is a house located between Mocksville and Lexington, North Carolina, at the terminus of SR 1812 (Peter Hairston Rd.) on the Yadkin River in Davie County, North Carolina. It is a U.S. National Historic Landmark, designated in 1978 for its architecture.