Destination X (2006) was a professional wrestling pay-per-view (PPV) event produced by Total Nonstop Action Wrestling (TNA), which took place on March 12, 2006 from the Impact Zone in Orlando, Florida. It was the second event under the Destination X chronology. Eight matches were featured on the event's card. In October 2017, with the launch of the Global Wrestling Network, the event became available to stream on demand.