About: Devimistat

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Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML).

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug drug
rdfs:label	Devimistat (en)
rdfs:comment	Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML). (en)
foaf:depiction
dcterms:subject	Carboxylic acids Thioethers Experimental cancer drugs
Wikipage page ID	62034187 (xsd:integer)
Wikipage revision ID	1030997838 (xsd:integer)
Link from a Wikipage to another Wikipage	Derivative (chemistry) Carboxylic acids Thioethers Orphan drug Enzymes Myelodysplastic syndrome Experimental cancer drugs dbr:Lipoic_acid Pancreatic cancer Peripheral T-cell lymphoma Burkitt's lymphoma Tricarboxylic acid cycle U.S. Food and Drug Administration Acute myeloid leukemia Drug development International Nonproprietary Name Chemotherapy Mechanism of action FOLFIRINOX dbr:Anti-mitochondrial
sameAs	Devimistat Devimistat
dbp:wikiPageUsesTemplate	dbt:Infobox_drug dbt:Reflist
thumbnail	wiki-commons:Special:FilePath/Devimistat.svg?width=300
c	22 (xsd:integer)
CAS number	95809 (xsd:integer)
ChEMBL	3186849 (xsd:integer)
ChemSpiderID	28189062 (xsd:integer)
DrugBank	12109 (xsd:integer)
H	28 (xsd:integer)
IUPAC name	68 (xsd:integer)
legal status	Investigational (en)
O	2 (xsd:integer)
PubChem	24770514 (xsd:integer)
s	2 (xsd:integer)
SMILES	C1=CC=CCSCCCSCC2=CC=CC=C2 (en)
StdInChI	1 (xsd:integer)
StdInChIKey	ZYRLHJIMTROTBO-UHFFFAOYSA-N (en)
synonyms	CPI-613 (en)
UNII	E76113IR49 (en)
has abstract	Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML). Devimistat's mechanism of action differs from other drugs, operating on the tricarboxylic acid cycle and inhibiting enzymes involved with cancer cell energy metabolism. A lipoic acid derivative different from standard cytotoxic chemotherapy, devimistat is currently being studied in combination with modified FOLFIRINOX to treat various solid tumors and heme malignancies. (en)
prov:wasDerivedFrom	wikipedia-en:Devimistat?oldid=1030997838&ns=0
page length (characters) of wiki page	4157 (xsd:nonNegativeInteger)
CAS number	95809-78-2
ChEMBL	3186849
DrugBank	12109
FDA UNII code	E76113IR49
PubChem	24770514
foaf:isPrimaryTopicOf	wikipedia-en:Devimistat
is Link from a Wikipage to another Wikipage of	C22H28O2S2 CPI-613
is Wikipage redirect of	C22H28O2S2 CPI-613
is foaf:primaryTopic of	wikipedia-en:Devimistat

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