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About: Dornase alfa     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:Agent114778436yago:CausalAgent100007347yago:Drug103247620yago:Matter100020827yago:PhysicalEntity100001930drugyago:Substance100020090yago:WikicatDrugsActingOnTheRespiratorySystemumbel-rc:DrugProduct New Facet based on Instances of this Class

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cystic fibrosis patients and reduces viscosity in the lungs, promoting improved clearance of secretions. This protein therapeutic agent is produced in Chinese hamster ovary cells.