The E. O. Grosvenor House, also known as the Gamble House, is located at 211 Maumee Street in Jonesville, Michigan. It was built as a private home for Ebenezer O. Grosvenor, and now operates as the Grosvenor House Museum. It was designated a Michigan State Historic Site and listed on the National Register of Historic Places in 1977. It is considered one of the most magnificent residences in Michigan.