About: EIF4A

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An Entity of Type : umbel-rc:ProteinMolecule, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
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The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. In addition these proteins are helicases that function to unwind double-stranded RNA.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein yago:Abstraction100002137 yago:Arrangement107938773 yago:Gene105436752 yago:Group100031264 yago:Ordering108456993 protein yago:Sequence108459252 yago:Series108457976 yago:WikicatEukaryoteGenes umbel-rc:ProteinMolecule
rdfs:label	EIF4A (en) EIF4A (zh)
rdfs:comment	The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. In addition these proteins are helicases that function to unwind double-stranded RNA. (en) 真核起始因子4A（英語：eukaryotic translation Initiation Factor 4A，简称为eIF4A）是一种ATP依赖性RNA结合蛋白，一种RNA依赖性ATP酶，和一种RNA解旋酶，它在真核翻译起始进程中发挥重要作用。它被认为可以解开mRNA的5'端非翻译区的二级和三级结构，以使核糖体的附着更容易，同时允许核糖体进行起始密码子扫描。 eIF4A在人体中有三个亚型：eIF4A-1、eIF4A-2和eIF4A-3。 (zh)
foaf:name	eukaryotic translation initiation factor 4A, isoform 1 (en) eukaryotic translation initiation factor 4A, isoform 2 (en) eukaryotic translation initiation factor 4A, isoform 3 (en)
name	EIF4A1 EIF4A2 EIF4A3
dcterms:subject	Human proteins
Wikipage page ID	20246302 (xsd:integer)
Wikipage revision ID	1107425063 (xsd:integer)
Link from a Wikipage to another Wikipage	Rocaglamide Messenger RNA Human proteins Gene expression Protein synthesis Mature messenger RNA Helicase Amino acid DEAD box Eukaryote Protein RNA Guanosine triphosphate Hippuristanol EIF3 EIF4A1 EIF4A2 EIF4A3 EIF4B EIF4E EIF4H Ternary complex Model organism Regulatory sequence Start codon Methionine Cereal germ Sea urchin Eukaryotic initiation factor Eukaryotic initiation factor 4F Ribosome Molecular biology Phosphorylation TRNA Secondary structure 40S EIF4F Splicing (genetics)
sameAs	EIF4A EIF4A EIF4A EIF4A EIF4A
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Short_description dbt:Infobox_protein dbt:Lowercase
OMIM	601102 (xsd:integer) 602641 (xsd:integer) 608546 (xsd:integer)
AltSymbols	DDX48 (en) EIF4A (en) EIF4F (en)
ECnumber	3.600000 (xsd:double)
symbol	EIF4A1 EIF4A2 EIF4A3
UniProt	P38919 (en) P60842 (en) Q14240 (en)
has abstract	The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. In addition these proteins are helicases that function to unwind double-stranded RNA. (en) 真核起始因子4A（英語：eukaryotic translation Initiation Factor 4A，简称为eIF4A）是一种ATP依赖性RNA结合蛋白，一种RNA依赖性ATP酶，和一种RNA解旋酶，它在真核翻译起始进程中发挥重要作用。它被认为可以解开mRNA的5'端非翻译区的二级和三级结构，以使核糖体的附着更容易，同时允许核糖体进行起始密码子扫描。 eIF4A在人体中有三个亚型：eIF4A-1、eIF4A-2和eIF4A-3。 (zh)
Arm	p (en) q (en)
band	13 (xsd:integer) 25.300000 (xsd:double) 28 (xsd:integer)
Chromosome	3 (xsd:integer) 17 (xsd:integer)
EntrezGene	1973 (xsd:integer) 1974 (xsd:integer) 9775 (xsd:integer)
HGNCid	3282 (xsd:integer)

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