Edward John O'Dea (November 23, 1856 – December 25, 1932) was an American prelate of the Catholic Church. He served as bishop of the Diocese of Nesqually in Washington State from 1896 until 1907. When the Vatican renamed the diocese as the Diocese of Seattle in 1907, O'Dea served as its bishop until his death in 1932. O'Dea was responsible for the construction of St. James Cathedral in Seattle, Washington.