Edwin Willits (also Willets) (April 24, 1830 – October 22, 1896) was a politician from the U.S. state of Michigan. Willits served as prosecuting attorney of Monroe County, Republican from Michigan's 2nd congressional district for the 45th, 46th, and 47th Congresses. Presidents of Michigan State Normal School (now Eastern Michigan University) and the State Agricultural College (now Michigan State University). The first Assistant U.S. Secretary of Agriculture under Jeremiah McLain Rusk for Benjamin Harrison's administration.