Elrod is an unincorporated community in Tuscaloosa County, Alabama, United States. Elrod is located on County Route 15, 13.3 miles (21.4 km) west-northwest of Tuscaloosa. Elrod has a post office with ZIP code 35458. Elrod was renamed from Sipsey Turnpike in 1898 after the Mobile and Ohio Railroad reached the community. It was named in honor of William W. Elrod, a local physician.