About: Eltoprazine

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An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
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Eltoprazine (developmental code name DU-28,853) is a serotonergic drug of the phenylpiperazine class which is described as a serenic or antiaggressive agent. It acts as an agonist of the serotonin 5-HT1A and 5-HT1B receptors and as an antagonist of the serotonin 5-HT2C receptor. The drug is closely related to fluprazine and batoprazine, which are similarly acting agents, and is also a known chemical precursor to S-15535 and lecozotan. Eltoprazine is or was under development for the treatment of aggression, attention deficit hyperactivity disorder (ADHD), cognition disorders, and drug-induced dyskinesia, but no recent development has been reported for these indications as of February 2022. It was also under development for the treatment of psychotic disorders, but development for this indic

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:Adversary109773245 yago:CausalAgent100007347 yago:LivingThing100004258 yago:Object100002684 yago:Organism100004475 yago:Person100007846 yago:PhysicalEntity100001930 yago:YagoLegalActor yago:YagoLegalActorGeo drug yago:Whole100003553 yago:Wikicat5-HT2CAntagonists umbel-rc:DrugProduct
rdfs:label	Eltoprazine (en)
rdfs:comment	Eltoprazine (developmental code name DU-28,853) is a serotonergic drug of the phenylpiperazine class which is described as a serenic or antiaggressive agent. It acts as an agonist of the serotonin 5-HT1A and 5-HT1B receptors and as an antagonist of the serotonin 5-HT2C receptor. The drug is closely related to fluprazine and batoprazine, which are similarly acting agents, and is also a known chemical precursor to S-15535 and lecozotan. Eltoprazine is or was under development for the treatment of aggression, attention deficit hyperactivity disorder (ADHD), cognition disorders, and drug-induced dyskinesia, but no recent development has been reported for these indications as of February 2022. It was also under development for the treatment of psychotic disorders, but development for this indic (en)
foaf:depiction
dcterms:subject	Eltoprazines 5-HT1B agonists Benzodioxins Experimental drugs Piperazines Serotonin receptor agonists 5-HT1A agonists 5-HT2C antagonists
Wikipage page ID	22568440 (xsd:integer)
Wikipage revision ID	1107566394 (xsd:integer)
Link from a Wikipage to another Wikipage	Eltoprazines Batoprazine Antagonist 5-HT1B agonists Benzodioxins Experimental drugs Piperazines Serotonin receptor agonists S-15535 Lecozotan 5-HT1A agonists 5-HT2C antagonists Aggression Drug Aggressive Agonist Fluprazine Precursor (chemistry) Attention deficit hyperactivity disorder Phenylpiperazine Solvay S.A. Serotonergic dbr:Serotonin Serenic Drug-induced dyskinesia Psychotic disorder 5-HT1A 5-HT1B 5-HT2C Cognition disorder
Link from a Wikipage to an external page	https://adisinsight.springer.com/drugs/800000719
sameAs	Eltoprazine Eltoprazine Eltoprazine Eltoprazine Eltoprazine Eltoprazine Eltoprazine
dbp:wikiPageUsesTemplate	dbt:Commonscatinline dbt:Infobox_drug dbt:Piperazines dbt:Reflist dbt:Serotonin_receptor_modulators dbt:Short_description dbt:Fdacite
thumbnail	wiki-commons:Special:FilePath/Eltoprazine.png?width=300
c	12 (xsd:integer)
CAS number	98224 (xsd:integer)
ChEMBL	282614 (xsd:integer)
ChemSpiderID	59265 (xsd:integer)
H	16 (xsd:integer)
IUPAC name	1 (xsd:integer)
n	2 (xsd:integer)
O	2 (xsd:integer)
PubChem	65853 (xsd:integer)
SMILES	C1CNC2=C3COCCO3 (en)
StdInChI	1 (xsd:integer)
StdInChIKey	WVLHGCRWEHCIOT-UHFFFAOYSA-N (en)
synonyms	DU-28,853; DU-28853 (en)
UNII	510 (xsd:integer)
has abstract	Eltoprazine (developmental code name DU-28,853) is a serotonergic drug of the phenylpiperazine class which is described as a serenic or antiaggressive agent. It acts as an agonist of the serotonin 5-HT1A and 5-HT1B receptors and as an antagonist of the serotonin 5-HT2C receptor. The drug is closely related to fluprazine and batoprazine, which are similarly acting agents, and is also a known chemical precursor to S-15535 and lecozotan. Eltoprazine is or was under development for the treatment of aggression, attention deficit hyperactivity disorder (ADHD), cognition disorders, and drug-induced dyskinesia, but no recent development has been reported for these indications as of February 2022. It was also under development for the treatment of psychotic disorders, but development for this indication was discontinued. Eltoprazine was originated by Solvay and was developed by Elto Pharma, PsychoGenics, and Solvay. (en)
gold:hypernym	Drug
prov:wasDerivedFrom	wikipedia-en:Eltoprazine?oldid=1107566394&ns=0
page length (characters) of wiki page	4057 (xsd:nonNegativeInteger)
CAS number	98224-03-4
ChEMBL	282614
FDA UNII code	510M006KO6
PubChem	65853
foaf:isPrimaryTopicOf	wikipedia-en:Eltoprazine
is Link from a Wikipage to another Wikipage of	Enciprazine

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