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Epidermolysis bullosa acquisita, also known as acquired epidermolysis bullosa, is a longterm autoimmune blistering skin disease. It generally presents with fragile skin that blisters and becomes red with or without trauma. Marked scarring is left with thin skin, milia and nail changes. It typically begins around age 50-years. It is caused by antibodies to type VII collagen within anchoring fibril structures located at the dermoepidermal junction in skin. Damaged skin may become infected.

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rdfs:label
  • انحلال الجلد الفقاعي المكتسب (ar)
  • Epidermolysis bullosa acquisita (en)
  • Epidermolisi bollosa acquisita (it)
rdfs:comment
  • انحلال الجلد الفقاعي المكتسب(بالإنجليزي: Epidermolysis bullosa acquisita) هو مرض من أمراض المناعة الذاتية ينتج نتيجة تكون مستضدات لنوع الالكولاجين السابع. يظهر على شكل تقرحات مزمنة في منطقةالألياف وهي منطقة اتصال البشرة بالأدمة (ar)
  • L'epidermolisi bollosa acquisita è una malattia immuno-bollosa caratterizzata dalla comparsa di bolle subepidermiche. (it)
  • Epidermolysis bullosa acquisita, also known as acquired epidermolysis bullosa, is a longterm autoimmune blistering skin disease. It generally presents with fragile skin that blisters and becomes red with or without trauma. Marked scarring is left with thin skin, milia and nail changes. It typically begins around age 50-years. It is caused by antibodies to type VII collagen within anchoring fibril structures located at the dermoepidermal junction in skin. Damaged skin may become infected. (en)
foaf:name
  • Epidermolysis bullosa acquisita (en)
name
  • Epidermolysis bullosa acquisita (en)
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dbp:wikiPageUsesTemplate
DiseasesDB
ICD
MeshID
  • D016107 (en)
Orphanet
synonyms
  • Acquired epidermolysis bullosa (en)
has abstract
  • انحلال الجلد الفقاعي المكتسب(بالإنجليزي: Epidermolysis bullosa acquisita) هو مرض من أمراض المناعة الذاتية ينتج نتيجة تكون مستضدات لنوع الالكولاجين السابع. يظهر على شكل تقرحات مزمنة في منطقةالألياف وهي منطقة اتصال البشرة بالأدمة (ar)
  • Epidermolysis bullosa acquisita, also known as acquired epidermolysis bullosa, is a longterm autoimmune blistering skin disease. It generally presents with fragile skin that blisters and becomes red with or without trauma. Marked scarring is left with thin skin, milia and nail changes. It typically begins around age 50-years. It is caused by antibodies to type VII collagen within anchoring fibril structures located at the dermoepidermal junction in skin. Damaged skin may become infected. Diagnosis is by observing the persistence of the condition, direct immunofluorescence, and detecting autoantibodies against type VII collagen. It can appear similar to porphyria cutanea tarda, pemphigoid, pemphigus, dermatitis herpetiformis, or blistering drug eruption. The condition is longterm and has no cure. A good response may be seen with corticosteroids, either alone or combined with azathioprine or dapsone. It is rare, with around 0.08 to 0.5 new cases per million people per year, and it affects males and females equally. (en)
  • L'epidermolisi bollosa acquisita è una malattia immuno-bollosa caratterizzata dalla comparsa di bolle subepidermiche. (it)
eMedicineSubj
  • article (en)
eMedicineTopic
ICD9
  • 694.8
eMedicine subject
  • article (en)
eMedicine topic
  • 1063083 (en)
MeSH ID
  • D016107
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page length (characters) of wiki page
DiseasesDB
  • 4338
ICD10
  • L12.3
ORPHA
  • 46487
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