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About: Eptifibatide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatAmidesyago:Abstraction100002137yago:Amide114724264yago:Chemical114806838yago:Compound114818238yago:Material114580897yago:Matter100020827yago:OrganicCompound114727670yago:Part113809207yago:Peptide114743046yago:PhysicalEntity100001930yago:Relation100031921drugyago:Substance100019613yago:WikicatPeptidesumbel-rc:DrugProduct New Facet based on Instances of this Class

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a disintegrin protein (P22827) found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.