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Estradiol benzoate (EB), sold under the brand name Progynon-B among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in the treatment of gynecological disorders. It is also used in the treatment of prostate cancer in men. Estradiol benzoate is used in veterinary medicine as well. When used clinically, the medication is given by injection into muscle usually two to three times per week.

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  • Estradiol benzoate (en)
  • Estradiolbenzoat (de)
  • 安息香酸エストラジオール (ja)
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  • Estradiolbenzoat ist eine synthetische Verbindung aus der Stoffklasse der Steroidhormone. Es ist der Ester des natürlich vorkommenden weiblichen Sexualhormons Estradiol mit Benzoesäure. (de)
  • 安息香酸エストラジオール(あんそくこうさんエストラジオール、英: Estradiol benzoate)は、エストラジオールの安息香酸エステルの一種。最初に製品化されたエストロゲン製剤であり、1936年にシエーリング・カールバウム(Schering-Kahlbaun)が特許を取得して、Progynon-Bの商品名で注射用油性製剤として販売された。現在では薬物動態学の点から、低頻度の投与で済む (estradiol cypionate) や (estradiol valerate) も使われている。融点は195℃、ラットへの皮下投与実験での半数致死量(TDL0)は、500μg/kg。 (ja)
  • Estradiol benzoate (EB), sold under the brand name Progynon-B among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in the treatment of gynecological disorders. It is also used in the treatment of prostate cancer in men. Estradiol benzoate is used in veterinary medicine as well. When used clinically, the medication is given by injection into muscle usually two to three times per week. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol_levels_after_a_single_5_mg_intramuscular_injection_of_estradiol_esters.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol_levels_after_injections_of_estradiol,_estradiol_benzoate,_estradiol_valerate,_and_estradiol_undecylate_in_women.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Idealized_curves_of_estradiol_levels_after_injection_of_different_estradiol_esters_in_women.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol_benzoate.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol_benzoate_molecule_ball.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Estradiol_levels_after_single_intramuscular_injections_of_different_doses_of_estradiol_benzoate_in_premenopausal_women.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Vaginal_cornification_with_a_single_intramuscular_injection_of_different_estradiol_esters_in_women.png
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