Ezra L'Hommedieu (August 30, 1734 – September 27, 1811) was an American lawyer and statesman from Southold, New York in Suffolk County, Long Island. He was a delegate for New York to the Continental Congress (1779 to 1783) and again in 1788. His national offices overlapped with those he served in the state: in the State Assembly (1777-1783) and in the state senate (1784-1792) and (1794-1809); he was a member of the state constitutional convention in 1801. He also served in local offices, as clerk of Suffolk County from January 1784 to March 1810 and from March 1811 until his death that year. He was a regent of the University of the State of New York.