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Fibroblast growth factor 14 is a biologically active protein that in humans is encoded by the FGF14 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.

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  • FGF14 (ar)
  • FGF14 (en)
  • FGF14 (uk)
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  • FGF14‏ (Fibroblast growth factor 14) هوَ بروتين يُشَفر بواسطة جين FGF14 في الإنسان. (ar)
  • Fibroblast growth factor 14 is a biologically active protein that in humans is encoded by the FGF14 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. (en)
  • FGF14 (англ. Fibroblast growth factor 14) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 13-ї хромосоми. Довжина поліпептидного ланцюга білка становить 247 амінокислот, а молекулярна маса — 27 702. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
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  • FGF14‏ (Fibroblast growth factor 14) هوَ بروتين يُشَفر بواسطة جين FGF14 في الإنسان. (ar)
  • Fibroblast growth factor 14 is a biologically active protein that in humans is encoded by the FGF14 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. FGF14 is mainly expressed in the central nervous system and is associated with neurodegenerative diseases such as spinocerebellar ataxia (SAC27). FGF14 deficiency also impairs the maturation of cells in the hippocampus, which is possibly related to the development of schizophrenia. (en)
  • FGF14 (англ. Fibroblast growth factor 14) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 13-ї хромосоми. Довжина поліпептидного ланцюга білка становить 247 амінокислот, а молекулярна маса — 27 702. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Кодований геном білок за функцією належить до факторів росту. Задіяний у такому біологічному процесі, як альтернативний сплайсинг. Локалізований у ядрі. (uk)
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