Filaggrin (filament aggregating protein) is a filament-associated protein that binds to keratin fibers in epithelial cells. Ten to twelve filaggrin units are post-translationally hydrolyzed from a large profilaggrin precursor protein during terminal differentiation of epidermal cells. In humans, profilaggrin is encoded by the FLG gene, which is part of the (SFTP) family within the epidermal differentiation complex on chromosome 1q21.
Attributes | Values |
---|---|
rdf:type | |
rdfs:label |