State Road 48 (SR 48) was an east–west state highway that ran from U.S. Highway 41 in Floral City, Florida, to Florida State Road 19 in Howey-in-the-Hills, Florida. In the last years of the route's existence, it was a 2.167 miles (3.487 km) state road in Bushnell, Florida, which ran from Interstate 75 (I-75) at exit 314 to U.S. Highway 301 (US 301). Today, all segments are designated County Road 48 (CR 48) where they are under county maintenance. Segments in Sumter County are part of the Scenic Sumter Heritage Byway.