About: Flurothyl

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Flurothyl (Indoklon) (IUPAC names: 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane or bis(2,2,2-trifluoroethyl) ether) is a volatile liquid drug from the halogenated ether family, related to inhaled anaesthetic agents such as diethyl ether, but having the opposite effects, acting as a stimulant and convulsant. A clear and stable liquid, it has a mild ethereal odor whose vapors are non-flammable. It is excreted from the body by the lungs in an unchanged state. The main current use of flurothyl is in scientific research for inducing seizures in laboratory animals.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:WikicatStimulants yago:Abstraction100002137 yago:Cognition100023271 yago:Element114840755 yago:Information105816287 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:PsychologicalFeature100023100 yago:Quintessence114847103 yago:Relation100031921 drug yago:Stimulation105827684 yago:Substance100019613 yago:WikicatEthers umbel-rc:DrugProduct
rdfs:label	Flurothyl (en)
rdfs:comment	Flurothyl (Indoklon) (IUPAC names: 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane or bis(2,2,2-trifluoroethyl) ether) is a volatile liquid drug from the halogenated ether family, related to inhaled anaesthetic agents such as diethyl ether, but having the opposite effects, acting as a stimulant and convulsant. A clear and stable liquid, it has a mild ethereal odor whose vapors are non-flammable. It is excreted from the body by the lungs in an unchanged state. The main current use of flurothyl is in scientific research for inducing seizures in laboratory animals. (en)
foaf:depiction
dcterms:subject	Ethers GABAA receptor negative allosteric modulators Organofluorides Stimulants Antidepressants Convulsants
Wikipage page ID	19885618 (xsd:integer)
Wikipage revision ID	1096260552 (xsd:integer)
Link from a Wikipage to another Wikipage	Electrophysiology Memory improvement Anterograde amnesia Retrograde amnesia Inhalational anesthetic Ethers GABAA receptor negative allosteric modulators Organofluorides Stimulants Electroconvulsive therapy Convulsant Halogenated ether Positive allosteric modulator Stimulant Theories of general anaesthetic action Antidepressants Fluorine Convulsants Isoflurane Isoflurothyl dbr:Diethyl_ether Picrotoxin Sevoflurane Shock therapy (psychiatry) Volatility (chemistry) Pentetrazol Glycine receptors Inhaled anaesthetic agent
sameAs	Flurothyl Flurothyl Flurothyl Flurothyl Flurothyl Flurothyl Flurothyl
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:GABA_receptor_modulators dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Stdinchicite dbt:Convulsants
thumbnail	wiki-commons:Special:FilePath/Flurothyl.svg?width=300
ATC prefix	None (en)
c	4 (xsd:integer)
CAS number	333 (xsd:integer)
ChemSpiderID	9155 (xsd:integer)
density	1.404 (gramPerCubicCentimetre)
DrugBank	DB08969 (en)
F	6 (xsd:integer)
H	4 (xsd:integer)
IUPAC name	22 (xsd:integer) or (en) Bis ether (en)
molecular weight	182.064000 (xsd:double)
O	1 (xsd:integer)
PubChem	9528 (xsd:integer)
SMILES	COCCF (en)
StdInChI	1 (xsd:integer)
StdInChIKey	KGPPDNUWZNWPSI-UHFFFAOYSA-N (en)
synonyms	Hexafluorodiethyl ether (en)
UNII	9 (xsd:integer)
Verifiedfields	changed (en)
verifiedrevid	443825424 (xsd:integer)
Watchedfields	changed (en)
has abstract	Flurothyl (Indoklon) (IUPAC names: 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane or bis(2,2,2-trifluoroethyl) ether) is a volatile liquid drug from the halogenated ether family, related to inhaled anaesthetic agents such as diethyl ether, but having the opposite effects, acting as a stimulant and convulsant. A clear and stable liquid, it has a mild ethereal odor whose vapors are non-flammable. It is excreted from the body by the lungs in an unchanged state. Several compounds related to the halogenated ether anesthetics have similar convulsant effects rather than producing sedation, and this has been helpful in studying the mechanism of action of these drugs. The main current use of flurothyl is in scientific research for inducing seizures in laboratory animals. (en)

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