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Fominoben is an antitussive agent of the benzanilide class, formerly marketed under the name Noleptan. It binds poorly to the sigma-1 receptor, a receptor activated by many other antitussives. It is reported to have respiratory stimulant activity. Other research has indicated it may be an agonist at the benzodiazepine site of the GABAA receptor. It was introduced in Germany in 1973, in Italy in 1979, and in Japan in 1983.

AttributesValues
rdf:type
rdfs:label
  • Fominoben (en)
rdfs:comment
  • Fominoben is an antitussive agent of the benzanilide class, formerly marketed under the name Noleptan. It binds poorly to the sigma-1 receptor, a receptor activated by many other antitussives. It is reported to have respiratory stimulant activity. Other research has indicated it may be an agonist at the benzodiazepine site of the GABAA receptor. It was introduced in Germany in 1973, in Italy in 1979, and in Japan in 1983. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Fominoben.svg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
thumbnail
c
CAS number
ChEBI
ChEMBL
ChemSpiderID
Cl
DrugBank
  • DB08968 (en)
H
IUPAC name
  • N-[3-chloro-2-[[methyl-amino]methyl]phenyl]benzamide (en)
KEGG
  • D07988 (en)
n
O
PubChem
SMILES
  • CNCCN3CCOCC3 (en)
StdInChI
StdInChIKey
  • KSNNEUZOAFRTDS-UHFFFAOYSA-N (en)
tradename
  • Broncomenal, Deronyl, Finaten, Noleptan, Oleptan, Terion, Tosifar, Tussirama (en)
UNII
  • TJ2KK6NYJS (en)
has abstract
  • Fominoben is an antitussive agent of the benzanilide class, formerly marketed under the name Noleptan. It binds poorly to the sigma-1 receptor, a receptor activated by many other antitussives. It is reported to have respiratory stimulant activity. Other research has indicated it may be an agonist at the benzodiazepine site of the GABAA receptor. It was introduced in Germany in 1973, in Italy in 1979, and in Japan in 1983. Adverse effects include appetite suppression, nausea, vomiting, insomnia, irritability, and hallucinations. Rarer side effects include somnolence, dizziness, dry mouth, blurred vision, and urticaria. (en)
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page length (characters) of wiki page
alternative name
  • Broncomenal, Deronyl, Finaten, Noleptan, Oleptan, Terion, Tosifar, Tussirama (en)
CAS number
  • 18053-31-1
ChEBI
  • 135639
ChEMBL
  • 1697837
DrugBank
  • DB08968
FDA UNII code
  • TJ2KK6NYJS
KEGG
  • D07988
PubChem
  • 3407
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