Francisco Tiongson Duque III (Tagalog: [fɾɐnˈsisko ˈdukɛ]; born February 13, 1957) is a Filipino physician and government official who served as Secretary of Health in the Cabinet of President Rodrigo Duterte from 2017 to 2022, a position he had previously held from 2005 to 2009 in the Cabinet of President Gloria Macapagal Arroyo. From 2010 to 2015, he served as the chair of the Civil Service Commission.