The Gamaliel Thompson House is a former residential structure located at 101 Summit Street in the city of Hudson in westernmost Lenawee County, Michigan. It was designated as a Michigan State Historic State on February 22, 1974, and soon after listed on the National Register of Historic Places on April 3, 1975. It is located two blocks south of the Heman R. Goodrich House. The Thompson House now serves as the William G. Thompson House Museum.