George Robert Spence (born 6 April 1904, date of death unknown) was an English professional footballer who played as an outside forward. Born in Burnley, he started his career in local-league football with Colne Town. On 8 October 1927, Spence signed as an amateur with Football League Third Division North side Nelson and made his debut for the club in the 3–3 draw with Chesterfield later the same day alongside fellow new signing, goalkeeper William Bossons. He was awarded a professional contract two weeks later and went on to keep his place in the starting eleven for the following seven matches. Spence scored his first goal in senior football in the 4–2 win against Hartlepools United at Seedhill on 5 November 1927, a match which also featured a hat-trick from centre forward Buchanan Sharp.