State Route 376 (SR 376) is a 16.0-mile-long (25.7 km) east–west state highway that travels within portions of Lowndes and Echols counties in the southern part of the U.S. state of Georgia. It connects Clyattville with the Statenville area, via Lake Park. The roadway was built in the late 1950s and designated as SR 376 in 1972.