About: Germ line theory

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The germ-line theory was a proposed explanation for immunoglobulin diversity that proposed that each antibody was encoded in a separate germline gene. This does not occur in most species (including humans), but may occur in Elasmobranchs.

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rdfs:label	Germ line theory (en)
rdfs:comment	The germ-line theory was a proposed explanation for immunoglobulin diversity that proposed that each antibody was encoded in a separate germline gene. This does not occur in most species (including humans), but may occur in Elasmobranchs. (en)
dcterms:subject	Germ line cells Lymphocytes Obsolete immunology theories
Wikipage page ID	26434496 (xsd:integer)
Wikipage revision ID	798167309 (xsd:integer)
Link from a Wikipage to another Wikipage	Germ line cells Antibody Lymphocytes Obsolete immunology theories Elasmobranchs Immunoglobulin diversity
sameAs	Germ line theory Germ line theory Germ line theory Germ line theory
dbp:wikiPageUsesTemplate	dbt:Refimprove dbt:Reflist dbt:Immunology-stub
has abstract	The germ-line theory was a proposed explanation for immunoglobulin diversity that proposed that each antibody was encoded in a separate germline gene. This does not occur in most species (including humans), but may occur in Elasmobranchs. For decades microbiologists searched for a mechanism that could explain the large diversity of antibody structure. For this reason the germ line theory emerged. According to this theory, the genomes contributed by the germ cell, sperm and egg contained a large repertoire of immunoglobulin genes. It was clear that there should be a mechanism that help the antibody to have diversity and keep it constant. The germ line theory could not provide any explanation on this aspect. (en)
gold:hypernym	Explanation
prov:wasDerivedFrom	wikipedia-en:Germ_line_theory?oldid=798167309&ns=0
page length (characters) of wiki page	1337 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Germ_line_theory
is Link from a Wikipage to another Wikipage of	Superseded theories in science Germ-line theory Germline theory
is Wikipage redirect of	Germ-line theory Germline theory
is foaf:primaryTopic of	wikipedia-en:Germ_line_theory

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