German submarine U-322 was a Type VIIC/41 U-boat of Nazi Germany's Kriegsmarine during World War II. She carried out two patrols, sinking one ship of 5,149 gross register tons (GRT) and causing two others totaling 14,367 GRT to be declared total losses. The boat was sunk on 29 December 1944 by a Canadian corvette in the English Channel.