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Gliadorphin (also known as gluteomorphin) is an opioid peptide that is formed during digestion of the gliadin component of the gluten protein. It is usually broken down into amino acids by digestion enzymes. It has been hypothesized that children with autism have abnormal leakage from the gut of this compound. This is partly the basis for the gluten-free, casein-free diet. Abnormally high levels of gliadorphin have been found in the urine of autistic children via mass spectrometry testing.

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  • Gliadorphin (de)
  • Gliadorphin (en)
  • Gliadorfina (pl)
  • Gliadorfina (pt)
rdfs:comment
  • Gliadorphin, in einigen Publikationen auch als Gluteomorphin bezeichnet, ist ein exogenes Opioidpeptid, ein sogenanntes Exorphin, welches bei der Verdauung von in Gluten enthaltenem Gliadin entstehen kann. (de)
  • Gliadorphin (also known as gluteomorphin) is an opioid peptide that is formed during digestion of the gliadin component of the gluten protein. It is usually broken down into amino acids by digestion enzymes. It has been hypothesized that children with autism have abnormal leakage from the gut of this compound. This is partly the basis for the gluten-free, casein-free diet. Abnormally high levels of gliadorphin have been found in the urine of autistic children via mass spectrometry testing. (en)
  • A gliadorfina (também conhecida como gluteomorfina) é um formado durante a digestão do componente gliadina da proteína do glúten. Geralmente é dividido em aminoácidos pelas enzimas da digestão. Foi levantada a hipótese de que crianças com autismo têm vazamento anormal do intestino desse composto. Isso é parcialmente a base da dieta sem glúten e sem caseína. Níveis anormalmente altos de gliadorfina foram encontrados na urina de crianças autistas através de testes de espectrometria de massa. (pt)
  • Gliadorfina, gluteomorfina – organiczny związek chemiczny z grupy peptydów, który w organizmie ludzkim jest związkiem przejściowym w procesie trawienia , prolaminy występującej w pszenicy i życie. Jest rozkładana przez enzymy trawienne na aminokwasy. Gliadorfina nie jest obecnie zaliczana do opioidów, ale jest prekursorem egzorfin glutenowych spośród których dwie (o oznaczeniu A5 i C5) mogą nie być całkowicie trawione i mogą być peptydami opioidowymi. (pl)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Gliadorphin-7.svg
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  • Gliadorphin-7.svg (en)
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IUPACName
  • (L)-Tyrosyl-(L)-prolyl-(L)-glutaminyl-(L)-prolyl-(L)-glutaminyl-(L)-prolyl-(L)-phenylalanine (en)
OtherNames
  • Gluteomorphin; Gliadorphin-7 (en)
has abstract
  • Gliadorphin, in einigen Publikationen auch als Gluteomorphin bezeichnet, ist ein exogenes Opioidpeptid, ein sogenanntes Exorphin, welches bei der Verdauung von in Gluten enthaltenem Gliadin entstehen kann. (de)
  • Gliadorphin (also known as gluteomorphin) is an opioid peptide that is formed during digestion of the gliadin component of the gluten protein. It is usually broken down into amino acids by digestion enzymes. It has been hypothesized that children with autism have abnormal leakage from the gut of this compound. This is partly the basis for the gluten-free, casein-free diet. Abnormally high levels of gliadorphin have been found in the urine of autistic children via mass spectrometry testing. (en)
  • A gliadorfina (também conhecida como gluteomorfina) é um formado durante a digestão do componente gliadina da proteína do glúten. Geralmente é dividido em aminoácidos pelas enzimas da digestão. Foi levantada a hipótese de que crianças com autismo têm vazamento anormal do intestino desse composto. Isso é parcialmente a base da dieta sem glúten e sem caseína. Níveis anormalmente altos de gliadorfina foram encontrados na urina de crianças autistas através de testes de espectrometria de massa. (pt)
  • Gliadorfina, gluteomorfina – organiczny związek chemiczny z grupy peptydów, który w organizmie ludzkim jest związkiem przejściowym w procesie trawienia , prolaminy występującej w pszenicy i życie. Jest rozkładana przez enzymy trawienne na aminokwasy. Gliadorfina nie jest obecnie zaliczana do opioidów, ale jest prekursorem egzorfin glutenowych spośród których dwie (o oznaczeniu A5 i C5) mogą nie być całkowicie trawione i mogą być peptydami opioidowymi. Przed 2015 związek ten zaliczany był do peptydów opioidowych. Przypuszczano, że nie jest całkowicie trawiony, przedostaje się do krwi i jest obecny w moczu. Hipoteza ta ma odzwierciedlenie w nazwie potocznej tego peptydu: gluteomorfina (gliadyna, prekursor gliadorfiny jest jednym ze składników glutenu). (pl)
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alternative name
  • Gluteomorphin; Gliadorphin-7 (en)
IUPAC name
  • (L)-Tyrosyl-(L)-prolyl-(L)-glutaminyl-(L)-prolyl-(L)-glutaminyl-(L)-prolyl-(L)-phenylalanine (en)
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