Glycemic efficacy refers to the capacity of regulated glycemic levels to produce an effect in people with diabetes and heart disease. According to , and , "exenatide and liraglutide are synthetic GLP-1 agonists and have demonstrated glycemic efficacy (HbA1c reductions of between 0.7 and 2%) associated with mild weight loss." Glyburide, metformin and rosiglitazone have been assessed as a monotherapy in the durability of glycemic efficacy.
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