About: Glycoside hydrolase family 5     Goto   Sponge   NotDistinct   Permalink

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In molecular biology, glycoside hydrolase family 5 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

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rdfs:label
  • Glycoside hydrolase family 5 (en)
rdfs:comment
  • In molecular biology, glycoside hydrolase family 5 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. (en)
name
  • Cellulase (en)
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sameAs
dbp:wikiPageUsesTemplate
PROSITE
  • PDOC00565 (en)
SCOP
CAZy
  • GH5 (en)
InterPro
  • IPR001547 (en)
Pfam
  • PF00150 (en)
Pfam clan
  • CL0058 (en)
symbol
  • Cellulase (en)
has abstract
  • In molecular biology, glycoside hydrolase family 5 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. Glycoside hydrolase family 5 CAZY GH_5 comprises enzymes with several known activities including endoglucanase (EC 3.2.1.4); beta-mannanase (EC 3.2.1.78); exo-1,3-glucanase (EC 3.2.1.58); endo-1,6-glucanase (EC 3.2.1.75); xylanase (EC 3.2.1.8); endoglycoceramidase (EC 3.2.1.123); xanthanase. The microbial degradation of cellulose and xylans requires several types of enzymes. Fungi and bacteria produces a spectrum of cellulolytic enzymes (cellulases) and xylanases which, on the basis of sequence similarities, can be classified into families. One of these families is known as the cellulase family A or as the glycosyl hydrolases family 5. One of the conserved regions in this family contains a conserved glutamic acid residue which is potentially involved in the catalytic mechanism. In a recent study using Molecular Dynamics simulations, a considerable correlation between thermal stability and structural rigidity of members of family 5 with solved structures has been proved. (en)
Membranome family
OPM family
OPM protein
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Symbol
  • Cellulase
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