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About: HLA-DQ6     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatHLA-DQHaplotypes, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: speciesyago:Abstraction100002137yago:Collection107951464yago:Combination107963711yago:Group100031264yago:Haplotype105439582yago:WikicatHLA-DQHaplotypes New Facet based on Instances of this Class

HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the antibody recognition of β6 subset of DQ β-chains. The β-chain of DQ isoforms are encoded by HLA-DQB1 locus and DQ6 are encoded by the HLA-DQB1*06 allele group. This group currently contains many common alleles, DQB1*0602 is the most common. HLA-DQ6 and DQB1*06 are almost synonymous in meaning. DQ6 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. For DQ6, however, cis-isoform pairing only occurs with DQ1 α-chains. There are many haplotypes of DQ6.