About: HLA A1-B8 haplotype     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Haplotype105439582, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
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HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene haplotype that covers the MHC Class I region of the human major histocompatibility complex on chromosome 6. A multigene haplotype is set of inherited alleles covering several genes, or gene-alleles; common multigene haplotypes are generally the result of identity by descent from a common ancestor (share a recent common ancestor for that segment of the chromosome). Chromosomal recombination fragments multigene haplotypes as the distance to that ancestor increases in number of generations.

AttributesValues
rdf:type
rdfs:label
  • HLA A1-B8 haplotype (en)
rdfs:comment
  • HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene haplotype that covers the MHC Class I region of the human major histocompatibility complex on chromosome 6. A multigene haplotype is set of inherited alleles covering several genes, or gene-alleles; common multigene haplotypes are generally the result of identity by descent from a common ancestor (share a recent common ancestor for that segment of the chromosome). Chromosomal recombination fragments multigene haplotypes as the distance to that ancestor increases in number of generations. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/HLA-mini.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Ig_A.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PBB_Protein_C4A_image.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PBB_Protein_LTA_image.jpg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
Link from a Wikipage to an external page
sameAs
type1var
  • - (en)
type2var
  • - (en)
type3var
type4var
  • - (en)
type5var
  • Cw7 (en)
type6var
dbp:wikiPageUsesTemplate
thumbnail
alias
  • 1.0 (second)
  • "HL A1,8; HL A1,A8; HLA A1-B8; (en)
length
location
othertype
  • Serotype (en)
has abstract
  • HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene haplotype that covers the MHC Class I region of the human major histocompatibility complex on chromosome 6. A multigene haplotype is set of inherited alleles covering several genes, or gene-alleles; common multigene haplotypes are generally the result of identity by descent from a common ancestor (share a recent common ancestor for that segment of the chromosome). Chromosomal recombination fragments multigene haplotypes as the distance to that ancestor increases in number of generations. The haplotype can be written in an extended form covering the major histocompatibility loci as follows: HLA A*01:01 : Cw*07:01 : B*08:01 However, there are many other gene-alleles within the haplotype. In Europe A1-B8 is found, generally as part of the HLA A1-B8-DR3-DQ2 haplotype. This haplotype is 4.7 million nucleotides in length and the second longest haplotype identified within the human genome. In Africa A1-B8 and India A1-B8 is associated with other genes and other variants of A*01 and B*08 (en)
Chromosome
freqMax
  • >15.0% (en)
gene1name
gene1var
  • *0101 (en)
gene2name
gene2var
  • *0101 (en)
gene3name
  • HLA-A (en)
gene3var
  • *0101 (en)
gene4name
gene4var
  • *0101 (en)
gene5name
  • HLA-C (en)
gene5var
  • *0701 (en)
gene6name
  • HLA-B (en)
gene6var
  • *0801 (en)
haplotype
  • Class I, A1-Cw7-B8 (en)
image source
  • HLA region on chromosome 6 (en)
loci1name
  • to (en)
  • HLA-A (en)
  • HLA-F (en)
loci1rows
loci4name
  • HLA-E (en)
loci4rows
loci5name
  • Cw-B (en)
loci5rows
loci6name
  • - (en)
NumLoci
  • - (en)
Placement
  • right (en)
popMax
  • Western Ireland (en)
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