About: Hantavirus vaccine

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Hantavirus vaccine is a vaccine that protects in humans against hantavirus infections causing hantavirus hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). The vaccine is considered important as acute hantavirus infections are responsible for significant morbidity and mortality worldwide. It is estimated that about 1.5 million cases and 46,000 deaths occurred in China from 1950 to 2007. The number of cases is estimated at 32,000 in Finland from 2005 to 2010 and 90,000 in Russia from 1996 to 2006.

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rdf:type	yago:Abstraction100002137 yago:Attribute100024264 yago:Condition113920835 yago:IllHealth114052046 yago:Infection114174549 yago:PathologicalState114051917 yago:PhysicalCondition114034177 yago:WikicatHantavirusInfections drug yago:State100024720
rdfs:label	Hantavirusimpfstoff (de) Hantavirus vaccine (en)
rdfs:comment	Ein Hantavirusimpfstoff ist ein Impfstoff gegen Infektionen mit Hantaviren. (de) Hantavirus vaccine is a vaccine that protects in humans against hantavirus infections causing hantavirus hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). The vaccine is considered important as acute hantavirus infections are responsible for significant morbidity and mortality worldwide. It is estimated that about 1.5 million cases and 46,000 deaths occurred in China from 1950 to 2007. The number of cases is estimated at 32,000 in Finland from 2005 to 2010 and 90,000 in Russia from 1996 to 2006. (en)
dcterms:subject	Hantavirus infections Vaccines
Wikipage page ID	41027768 (xsd:integer)
Wikipage revision ID	1091161880 (xsd:integer)
Link from a Wikipage to another Wikipage	Vaccine-naive Hantavirus infections Gou virus Hantavirus hemorrhagic fever with renal syndrome Hantavirus pulmonary syndrome Hantavirus Vaccines List of vaccine topics Phases of clinical research Seoul virus
Link from a Wikipage to an external page	http://www.viprbrc.org/brc/home.do%3Fdecorator=bunya http://www.expasy.org/viralzone/all_by_species/213.html https://www.cdc.gov/ncidod/diseases/hanta/hps/noframes/phys/technicalinfoindex.htm http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003159 http://www.viprbrc.org/brc/viprStrainDetails.do%3FncbiAccession=AM998808&decorator=bunya&context=1312898403892
sameAs	Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine Hantavirus vaccine
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Vaccines
has abstract	Ein Hantavirusimpfstoff ist ein Impfstoff gegen Infektionen mit Hantaviren. (de) Hantavirus vaccine is a vaccine that protects in humans against hantavirus infections causing hantavirus hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). The vaccine is considered important as acute hantavirus infections are responsible for significant morbidity and mortality worldwide. It is estimated that about 1.5 million cases and 46,000 deaths occurred in China from 1950 to 2007. The number of cases is estimated at 32,000 in Finland from 2005 to 2010 and 90,000 in Russia from 1996 to 2006. The first hantavirus vaccine was developed in 1990 initially for use against Hantaan River virus which causes one of the most severe forms of HFRS. It is estimated that about two million doses of rodent brain or cell-culture derived vaccine are given in China every year. The wide use of this vaccine may be partly responsible for a significant decrease in the number of HFRS cases in China to less than 20,000 by 2007. Other hantaviruses for which the vaccine is used include Seoul (SEOV) virus. However the vaccine is thought not to be effective against European hantaviruses including Puumala (PUUV) and Dobrava-Belgrade (DOBV) viruses. The pharmaceutical trade name for the vaccine is Hantavax. As of 2012 no hantavirus vaccine have been approved for use in Europe or USA. A phase 2 study on a human HTNV/PUUV DNA hantavirus vaccine is ongoing. In addition to Hantavax three more vaccine candidates have been studied in I–II stage clinical trials. They include a recombinant vaccine and vaccines derived from HTNV and PUUV viruses. However, their prospects are unclear (en)
gold:hypernym	Vaccine
prov:wasDerivedFrom	wikipedia-en:Hantavirus_vaccine?oldid=1091161880&ns=0
page length (characters) of wiki page	3696 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Hantavirus_vaccine
is Link from a Wikipage to another Wikipage of	Timeline of human vaccines Dobrava-Belgrade orthohantavirus Hantaan orthohantavirus Hantavirus hemorrhagic fever with renal syndrome List of Korean inventions and discoveries Seoul orthohantavirus Hantavax
is Wikipage redirect of	Hantavax
is foaf:primaryTopic of	wikipedia-en:Hantavirus_vaccine

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