Heinrich Joseph Wetzer (Anzefahr, Hesse-Kassel (or Hesse-Cassel), 19 March 1801 – Freiburg, Baden, 5 November 1853) was a German Orientalist. His greatest achievement was the part he took in the production of the first edition of the Kirchenlexikon for which he drew up the Nomenclator and which he edited with Benedict Welte.