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In enzymology and molecular biology, a holo-[acyl-carrier-protein] synthase (ACPS, EC 2.7.8.7) is an enzyme that catalyzes the chemical reaction: CoA-[4'-phosphopantetheine] + apo-acyl carrier protein adenosine 3',5'-bisphosphate + holo-acyl carrier protein This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. It is also known as 4'-phosphopantetheinyl transferase after the group it transfers.

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  • Holo-(acyl-carrier-protein) synthase (en)
  • Holo-(acyl-carrier-protein) synthase (fr)
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  • In enzymology and molecular biology, a holo-[acyl-carrier-protein] synthase (ACPS, EC 2.7.8.7) is an enzyme that catalyzes the chemical reaction: CoA-[4'-phosphopantetheine] + apo-acyl carrier protein adenosine 3',5'-bisphosphate + holo-acyl carrier protein This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. It is also known as 4'-phosphopantetheinyl transferase after the group it transfers. (en)
  • L'holo-[acyl carrier protein] synthase, ou holo-ACP synthase (ACPS), est une transférase qui catalyse la réaction chimique : Coenzyme A + apo-[acyl-carrier-protein] adénosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. Elle utilise le cation de magnésium Mg2+ comme cofacteur. Elle finalise la biosynthèse de l'acyl carrier protein en liant la phosphopantéthéine d'une coenzyme A à un résidu de sérine de l'apoprotéine pour former l'holoprotéine fonctionnelle. (fr)
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  • phosphopantetheinyltransferase (en)
name
  • ACPS (en)
  • phosphopantetheinyltransferase (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/5xuk.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1qr0_EBI.jpg
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  • crystal structure of the 4'-phosphopantetheinyl transferase sfp-coenzyme a complex (en)
  • holo-[acyl-carrier-protein] synthase trimer, Helicobacter pylori (en)
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InterPro
  • IPR008278 (en)
IUBMB EC number
Pfam
  • PF01648 (en)
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