"Homer Simpson in: 'Kidney Trouble'" is the eighth episode of the tenth season of the American animated television series The Simpsons. It first aired on the Fox network in the United States on December 6, 1998. In the episode Grampa's kidneys explode, leaving him in urgent need of a donor. His son Homer initially agrees to donate one of his kidneys, but after hearing of side effects of only having one kidney, he begins to have second thoughts about the operation.