Humphrey Bate (May 25, 1875 – June 12, 1936) was an American harmonica player and string band leader. He was the first musician to play old-time music on Nashville-area radio. Bate and his band, which had been given the name "Dr. Humphrey Bate & His Possum Hunters" by Opry founder George D. Hay, were regulars on the Grand Ole Opry until Bate's death in 1936. The band's recordings, while scant, are considered some of the most distinctive and complex string band compositions in the old-time genre.