Idiopathic giant-cell myocarditis (IGCM) is a cardiovascular disease of the muscle of the heart (myocardium). The condition is rare; however, it is often fatal and there is no proven cure because of the unknown nature of the disorder. It is suggested to be caused by T-lymphocytes.
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| - التهاب العضلة القلبية ذات الخلية العملاقة مجهولة السبب (ar)
- Idiopathic giant-cell myocarditis (en)
- Myocardite à cellules géantes (fr)
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| - التهاب عضلة القلب ذات الخلايا العملاقة مجهولة السبب (IGCM) (بالإنجليزية: Idiopathic giant-cell myocarditis) هو شكل نادر وشديد لالتهاب عضلة القلب مجهول السبب الا أن 20٪ من الاصابات تتعلق بأمراض المناعة الذاتية خصوصاً عند الأطفاليصاحب الالتهاب ارتشاح كبير للخلايا المناعية أهمها الخلايا العملاقة وخلايا التهابية أخرى حيث تسبب ضرر بالغ لعضلة القلب قد تؤدي في أغلب الاحيان إلى فشل القلب. يتميز المرض بمعدلات وفيات عالية قد تصل إلى حوالي 70٪. (ar)
- La myocardite à cellules géantes est une forme rare de myocardite, très souvent fatale , caractérisée par l'infiltration du muscle cardiaque par des cellules géantes. (fr)
- Idiopathic giant-cell myocarditis (IGCM) is a cardiovascular disease of the muscle of the heart (myocardium). The condition is rare; however, it is often fatal and there is no proven cure because of the unknown nature of the disorder. It is suggested to be caused by T-lymphocytes. (en)
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| - Idiopathic giant-cell myocarditis (en)
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| - Idiopathic giant-cell myocarditis (en)
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| - Myocardium is affected by this condition (en)
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| - التهاب عضلة القلب ذات الخلايا العملاقة مجهولة السبب (IGCM) (بالإنجليزية: Idiopathic giant-cell myocarditis) هو شكل نادر وشديد لالتهاب عضلة القلب مجهول السبب الا أن 20٪ من الاصابات تتعلق بأمراض المناعة الذاتية خصوصاً عند الأطفاليصاحب الالتهاب ارتشاح كبير للخلايا المناعية أهمها الخلايا العملاقة وخلايا التهابية أخرى حيث تسبب ضرر بالغ لعضلة القلب قد تؤدي في أغلب الاحيان إلى فشل القلب. يتميز المرض بمعدلات وفيات عالية قد تصل إلى حوالي 70٪. (ar)
- Idiopathic giant-cell myocarditis (IGCM) is a cardiovascular disease of the muscle of the heart (myocardium). The condition is rare; however, it is often fatal and there is no proven cure because of the unknown nature of the disorder. IGCM frequently leads to death with a high rate of about 70% in first year. A patient with IGCM typically presents with symptoms of heart failure, although some may present initially with ventricular arrhythmia or heart block. Median age from the time the disease is diagnosed to the time of death is approximately 6 months. 90% of patients are either deceased by the end of 1 year or have received a heart transplant. Diagnosis is made by endomyocardial biopsy during heart catheterization. Biopsy shows multinucleated giant cells and thus the name. While previously cases universally required heart transplantation, recent studies show that two-thirds of patients can survive past one year with high doses of immunosuppressants such as prednisone and cyclosporine. The transplanted heart has a high chance of disease recurrence. Compared to lymphocytic (presumed viral) myocarditis, giant cell myocarditis is much more severe with much more rapid progression. It is suggested to be caused by T-lymphocytes. (en)
- La myocardite à cellules géantes est une forme rare de myocardite, très souvent fatale , caractérisée par l'infiltration du muscle cardiaque par des cellules géantes. (fr)
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