State Road 22 (SR 22) is an east–west discontinuous state road in the central part of the US state of Indiana. The western end of the western segment is in the town of Burlington, at SR 29. The highway passes through rural areas of Carroll and Howard counties, before ending in Kokomo. The eastern segment begins at an interchange with U.S. Route 31 (US 31) and US 35, in Kokomo, and heads east passing through towns and cities like Greentown, Gas City and Upland, before ending at SR 26. The western segment of SR 22 is concurrent with US 35 from Kokomo to Interstate 69 (I-69). The entire road covers a distance of about 45 miles (72 km), passing through mostly rural areas.