About: Interleukin-1 receptor

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Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible for transmitting the inflammatory effects of interleukin-1 (IL-1) while type II receptors may act as a suppressor of IL-1 activity by competing for IL-1 binding. Also opposing the effects of IL-1 is the IL-1 receptor antagonist (IL-1RA). The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein yago:BodyPart105220461 yago:Part109385911 yago:PhysicalEntity100001930 yago:Receptor105608868 yago:WikicatImmunoglobulinSuperfamilyCytokineReceptors protein yago:Structure105225602 yago:Thing100002452 umbel-rc:ProteinMolecule
rdfs:label	Receptor de la interleucina-1 (ca) Interleukin-1 receptor (en)
rdfs:comment	Un receptor de la interleucina-1 (IL-1R) és un que uneix la interleucina 1 (IL-1). Existeixen dues formes del receptor. El receptor tipus I és el principal responsable de transmetre els efectes inflamatoris de la IL-1, mentre que els receptors de tipus II poden actuar com a supressor de l'activitat de la IL-1 competint per la unió amb la IL-1. També s'oposa als efectes d'IL-1 l'antagonista dels receptors de la IL-1 (IL-1RA). La proteïna accessòria del receptor de la IL-1 és una proteïna transmembrana que interacciona amb IL-1R i és necessària per a la transducció del senyal de la IL-1. (ca) Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible for transmitting the inflammatory effects of interleukin-1 (IL-1) while type II receptors may act as a suppressor of IL-1 activity by competing for IL-1 binding. Also opposing the effects of IL-1 is the IL-1 receptor antagonist (IL-1RA). The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. (en)
rdfs:seeAlso	Interleukin-1 receptor family
foaf:name	interleukin 1 receptor accessory protein (en) interleukin 1 receptor, type I (en) interleukin 1 receptor, type II (en)
name	Interleukin 1 receptor, type I Interleukin 1 receptor, type II IL1RAP
dcterms:subject	Immunoglobulin superfamily cytokine receptors
Wikipage page ID	6208782 (xsd:integer)
Wikipage revision ID	1079711995 (xsd:integer)
Link from a Wikipage to another Wikipage	Cytokine receptor Inflammation Interleukin 1 receptor, type I Interleukin 1 receptor, type II Interleukin 1 receptor antagonist Immunoglobulin superfamily cytokine receptors IL1RAP Interleukin 1
sameAs	Interleukin-1 receptor Interleukin-1 receptor Interleukin-1 receptor Interleukin-1 receptor
dbp:wikiPageUsesTemplate	dbt:Membrane-protein-stub dbt:MeshName dbt:Reflist dbt:See_also dbt:Short_description dbt:Interleukin_receptor_modulators dbt:Infobox_protein dbt:Cytokine_receptors
OMIM	147810 (xsd:integer) 147811 (xsd:integer) 602626 (xsd:integer)
AltSymbols	IL-1RAcP, IL1R3, C3orf13 (en) IL1R, IL1RA (en) IL1RB (en)
symbol	Interleukin 1 receptor, type I Interleukin 1 receptor, type II IL1RAP
UniProt	P14778 (en) P27930 (en) Q9NPH3 (en)
has abstract	Un receptor de la interleucina-1 (IL-1R) és un que uneix la interleucina 1 (IL-1). Existeixen dues formes del receptor. El receptor tipus I és el principal responsable de transmetre els efectes inflamatoris de la IL-1, mentre que els receptors de tipus II poden actuar com a supressor de l'activitat de la IL-1 competint per la unió amb la IL-1. També s'oposa als efectes d'IL-1 l'antagonista dels receptors de la IL-1 (IL-1RA). La proteïna accessòria del receptor de la IL-1 és una proteïna transmembrana que interacciona amb IL-1R i és necessària per a la transducció del senyal de la IL-1. (ca) Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible for transmitting the inflammatory effects of interleukin-1 (IL-1) while type II receptors may act as a suppressor of IL-1 activity by competing for IL-1 binding. Also opposing the effects of IL-1 is the IL-1 receptor antagonist (IL-1RA). The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. (en)
Arm	q (en)
band	12 (xsd:integer) 28 (xsd:integer)
Chromosome	2 (xsd:integer) 3 (xsd:integer)
EntrezGene	3554 (xsd:integer) 3556 (xsd:integer) 7850 (xsd:integer)
HGNCid	5993 (xsd:integer) 5994 (xsd:integer) 5995 (xsd:integer)
RefSeq	NM_000877 (en) NM_134470 (en) NM_173343 (en)
gold:hypernym	Receptor
arm	q
band	12 28
chromosome	2 3
EntrezGene	3554 7850 3556
HGNCid	5993 5994 5995
RefSeq	NM_000877 NM_134470 NM_173343
UniProt	P14778 P27930 Q9NPH3
prov:wasDerivedFrom	wikipedia-en:Interleukin-1_receptor?oldid=1079711995&ns=0
page length (characters) of wiki page	3281 (xsd:nonNegativeInteger)
OMIM id	147810 (xsd:integer) 147811 (xsd:integer) 602626 (xsd:integer)
Symbol	IL-1RAcP, IL1R3, C3orf13 IL1R, IL1RA

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